After a decade honing its proprietary processes and constructing the scientific substantiation for its ingredient portfolio, Hofseth BioCare presents a portfolio of sustainable, upcycled options for a variety of well being end-points, together with iron standing, weight administration, irritation, bone and joint well being and coronary heart well being.
Amongst these options is ProGo, upcycled from Atlantic salmon (Salmo salar) through a mild enzymatic course of.
Talking with NutraIngredients on the current SupplySide West, Dr. Crawford Currie, HBC’s Head of Medical R&D, defined that the corporate’s investigation confirmed that it was a fraction of the peptides, the smallest peptides in ProGo, which are activating the GLP-1 receptor. The peptides additionally present pancreatic safety, so the place insulin is produced, he mentioned.
“The genesis of this examine was actually as a result of in our different scientific research, we might seen constant results round improved vitality and vitality,” he instructed us. “We might additionally seen constant weight reduction results of round 6% to 7% fats loss, and it was essential that it was fats loss. And we additionally noticed underlying this, improved metabolic markers, akin to a reducing of fasting blood glucose.”
Further evaluation revealed the activation of GLP-1, which Dr. Currie described as “thrilling”. The findings are printed in Marine Medication.
Commenting on the doses, Dr. Currie mentioned the HBC scientists have “gone down so far as 4 g a day and seen these very good, constant general well being advantages.
“However now we actually really feel we will drop that additional to assist, comfort, support formulation, and many others,” he added.
Ladies’s well being
Earlier work with ProGo revealed benefits around iron status and ferritin levels, with different research exhibiting advantages for intestine well being, all of that are matters which are entrance of thoughts within the girls’s well being class.
“It [women’s health] is strictly the place we really feel it is only a actually a pure match,” Dr. Currie mentioned. “And there might be many facets right here, however one we’re in all probability going to be beginning in is menopausal girls, the place, , typically there will be points round decreased vitality ranges, weight acquire, modifications within the intestine, together with the microbiome, but in addition intestine well being signs and in addition underlying metabolic modifications, together with will increase in irritation, will increase in fasting or in blood glucose.”
OmeGo
Dr. Currie additionally mentioned the corporate’s progress with its OmeGo salmon oil, which the corporate has lengthy said is extra than simply an omega-3-rich fish oil.
“Because the fish carcass is digested with the protein enzymes, actually the oil is simply liberated from the from the meat, and many others, after which that simply involves the floor of our tanks,” he defined. “It is simply taken off and bottled beneath nitrogen, and since we’re not processing it, and the way we do that is at low temperatures, the oil is extremely steady. It is received a pure four-year shelf life, simply bottled beneath nitrogen.”
Recent research has focused on lung health and respiratory function, and a just-completed examine with 120 folks explored the potential results of OmeGo round air pollution, sleep and respiratory well being.
“We’re trying particularly at sleep metrics, cough metrics and people are each self-scored metrics but in addition wearable machine seize, so we have now the subjective and the target measures,” he mentioned.
Supply: Marine Medication
2024, 22(11), 490; doi: 10.3390/md22110490
“Preliminary Exploration of the In Vitro Activation of GLP-1 and GIP Receptors and Pancreatic Islet Cell Safety by Salmon-Derived Bioactive Peptides”
Authors: C. Currie et al.
