“Rising proof demonstrates that osteoporosis may very well be prevalent in atherosclerotic sufferers and that interventions aimed toward stopping one situation might positively affect others, finally slowing down the development of growing older and enhancing the standard of life,” Marius Emil Rusu, researcher at Iuliu Hatieganu College of Drugs and Pharmacy in Romania, and colleagues wrote within the journal Vitamins.
Tackling well being dangers after the menopause
Ladies present process menopause have larger dangers of well being problems comparable to heart problems (CVD) and osteoporosis than youthful ladies as they see will increase in physique fats, insulin resistance and a discount in cardiovascular health. The CVD burden for these ladies is understudied, and one in three has an osteoporotic fracture throughout their lifetime, the authors famous.
Sustaining wholesome ranges of key nutritional vitamins is necessary for staving off CVD and bone circumstances in postmenopausal ladies. Examples embody vitamin D, which is absorbed via the pores and skin by way of ultraviolet B mild publicity or consumed as a part of the food plan from fatty fish, fish oil, egg yolks and vitamin Ok, which is present in darkish leafy-green greens and fermented meals.
Boosting consumption of those nutritional vitamins by way of food plan and dietary supplements might assist handle age-related well being dangers in postmenopausal ladies, famous Rusu and colleagues. Nonetheless, the results of co-treatment with vitamin D and vitamin Ok in postmenopausal ladies had not been reviewed till now, they mentioned.
Sustaining a nutritious diet
The authors assessed 31 earlier research on the function of vitamin D and vitamin Ok co-treatment in post-menopausal ladies, specializing in randomized managed parallel or crossover trial research. The commonest type of vitamin D used within the research was vitamin D3 with doses starting from 50 IU to 4,500 IU per day, and the commonest type of vitamin Ok among the many research was vitamin K1 with doses from 80 μg to 1 mg per day.
Based mostly on the investigations, Rusu et al. discovered that vitamin D and vitamin Ok labored synergistically to neutralize dangerous free radicals, decrease irritation and enhance bone power, along with stopping blood vessel calcification and sustaining wholesome blood stress ranges.
The conclusions emphasize the significance of sustaining a nutritious diet comparable to a Mediterranean food plan enhanced with nutritional vitamins Ok and D, which might stop age-associated ailments in menopausal ladies, the researchers wrote.
The researchers additionally acknowledged, nonetheless, that it might be tough for older folks to accumulate all their vitamins from dietary sources and due to this fact there may very well be important roles for vitamin dietary supplements along with wholesome consuming.
Commenting independently, Maciej Chichlowski, senior director of vitamin analysis at U.S. complement provider Shaklee Company, referred to as it fairly complete, contemplating the inclusion of knowledge from a lot of research throughout a variety of nations.
Encouraging dietary adjustments amongst postmenopausal ladies could be difficult, he mentioned, notably if consuming habits are deeply ingrained or if ladies have busy schedules. He additionally famous that the sort of change could be daunting and require substantial help and motivation.
“Entry to contemporary, wholesome meals could be restricted, particularly in meals deserts or rural areas, making it tough to observe the required food plan persistently,” he added. “Stress and different behavioral components can impede the adoption of a more healthy food plan.”
Wanting forward, he mentioned that many well being areas in postmenopausal ladies nonetheless require far more analysis together with the psychological results of menopause, sexual well being and the long-term advantages, dangers of hormone-replacement remedy, and the efficient prevention, early detection and therapy methods for osteoporosis.
Supply: Vitamins 2024, 16(14), 2356
“Investigating the Results and Mechanisms of Mixed Vitamin D and Ok Supplementation in Postmenopausal Ladies: An Up-to-Date Complete Evaluate of Medical Research”
doi: https://doi.org/10.3390/nu16142356
Authors: Marius Emil Rusu et al.
