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Gut health guinea pigs turned burgeoning business leaders

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October 11, 2025
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Gut health guinea pigs turned burgeoning business leaders


Once they launched their enterprise in 2017, twins and co-founders Lisa MacFarlane and Alana MacFarlane Kempner needed to take the thriller out of the intestine microbiome by finishing up public schooling on a big, evidence-based and entertaining scale.

The Gut Stuff was borne out of an ‘obsession’ with intestine well being that developed after lending themselves as ‘guinea pigs’ to the Predict twin examine led by Professor Tim Spector at Kings School, at which era they found that regardless of having equivalent DNA they solely share 30% to 40% the identical microbiota, answering lots of their lengthy held health-related questions.

What started as a YouTube collection of video interviews with intestine well being scientists and consultants, has develop into a multi-faceted empire together with a line of fiber-rich snack bars and drinks, an app, podcast, occasion roadshow, international company schooling program and extra.

Bars breaking boundaries

As their recognition inside the UK Quick Development 50 index proves, the business-savvy sisters have hit the mark with their fruit, nut and chicory root bars and their ‘fibre pop’ drinks, all of which include round 10 grams of fiber per serving.

The bars launched in 2021, and the drinks rolled-out earlier this 12 months, following within the enterprise mission to democratize intestine well being.

The Gut Stuff bar
The Intestine Stuff bar (The Intestine Stuff)

The entrepreneurs, who oversee a group of 5 employees, informed NutraIngredients they had been notably proud that the 90% YoY gross sales development for the bars has been natural, with nearly zero advertising and marketing spend.

“The retail information suggests our prospects are actually loyal, and whereas we anticipated the vast majority of customers to be 18 to 34 12 months outdated females, the demographics of patrons is actually extensive,” Lisa stated. “Importantly, we over-index within the non-affluent areas which is the very best factor for us as we needed to democratize useful snacks.”

The RRP is £1.30 per bar, or three for £3, which has been a problem to realize.

“I feel if we had realized how a lot of a quantity sport is was, we might not have made snack bars,” Lisa admitted. “It was an enormous goal versus revenue sport for some time, and it’s paid off now, nevertheless it was arduous, and it was solely actually potential as a result of we had so many various aspects to the enterprise which purchased us time.”

Alana added: “One spotlight needed to be once we each walked into Tesco with the children, and my daughter ran as much as the bars on shelf saying ‘mummy’s bars!’”

Unlocking new audiences

The recognition of the snacks is essentially because of the broader consumer awareness and interest in gut health and fiber, which They Intestine Stuff has helped amplify throughout the UK by way of its a number of initiatives.

The corporate’s company schooling program, which gives workers with intestine well being schooling and vitamin recommendation, has been one other large success, with purchasers reaching out from throughout the globe, together with Lloyds, Accenture, Lloyds, the RAF and Balfour Beatty.

And aiming to supply the general public with a one cease store for intestine well being questions, instruments, skilled recommendation and merchandise, The Intestine Stuff app has built-up 20,000 customers since its launch earlier this 12 months.

The Gut Stuff app
The Intestine Stuff app (The Intestine Stuff)

The app ‘gamifies intestine well being’ by serving to customers to hack their well being in 100 days by way of weight-reduction plan and way of life information assortment, weekly challenges, quizzes, recipes and product suggestions.

“We needed a platform that didn’t contain costly testing as a result of we all know that may typically create a worth barrier to those well being apps,” Alana defined.

The app additionally features a market of round 20 intestine well being merchandise alongside The Intestine Stuff’s personal snacks and drinks.

And the twins’ podcast, sponsored by Novonesis and Danone in collection one and two, delivers conversations between scientific consultants and celebrities to supply listeners with science-led information in an easy-listening and entertaining fashion.

“It’s been a headache primarily operating three enterprise collectively,” Lisa admitted, noting that there was methodology in what might look like insanity, and that in the end, their intestine feeling was all the time proper.

“We discovered a marketing strategy that we wrote again in 2017, and its fairly bang on, she stated. ”We now have been so mission led to make intestine well being as recurring as brushing your enamel.”

Alana added: “That’s undoubtedly coming to fruition. We saved saying ‘intestine well being will probably be large,’ and now it has crashed onto the shore, and we’re seeing that with the expansion of the corporate in addition to the broader conversations.”

Going international

Subsequent for the group is additional NPD within the food-to-go class, and past that, the duo has its sights on international enlargement.

“We now have an enormous quantity of natural web site viewers from the US so we all know there’s an urge for food for what we’re doing, and we’re simply ready for the proper time to maneuver the model over there,” Alana stated.

Whereas they’re proud to have reached this milestone with minimal advertising and marketing funding, the twins, who’ve each develop into mother and father in the previous couple of years, stated the achievement has not come with out its prices.

Lisa, who’s quickly to develop into a mum-of-two, stated: “Handing over your infants to another person to take care of at six weeks outdated as a result of you must get again to work is a big sacrifice, so profitable this form of recognition does assist to make us really feel our work, and the work of our unimaginable group, has been price it.”



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