Writing within the journal Vitamins, a group of college researchers explored the efficacy of eight weeks of supplementation with a Lumina365-branded complement developed by Slovenia-based Tosla Nutricosmetics.
“Probably the most thrilling discovering was the numerous lower in redness growth, demonstrated by way of goal, measurable outcomes,” mentioned Uroš Gotar, chief innovation officer at Tosla.
“A discount of 46.2% was noticed 24 hours after UVB publicity, indicating that Lumina365 enhances the pores and skin’s resilience in opposition to sun-induced redness, decreasing inflammatory response from the outset.”
The analysis was funded by the Slovenian Analysis and Innovation Company and Tosla.
A brand new layer of safety
Gotar famous that the research findings affirm that an oral complement can function a dependable addition to topical sunscreens, significantly in real-life conditions the place reapplication is usually forgotten.
“This stage of scientific proof provides significant credibility to the nutricosmetic class,” he mentioned.
“It introduces a brand new layer of safety that goes past conventional sunscreen and addresses a standard hole in solar care—that individuals usually neglect to reapply. Even simply 5 minutes of incidental solar publicity every day can accumulate over time, growing the danger of long-term pores and skin injury.”
He added that most individuals nonetheless solely affiliate sunscreen with summer time and holidays, not day by day routines, however that this product “shifts that mindset, providing constant, easy safety that redefines how we take into consideration solar care.”
The corporate labored to formulate, take a look at and validate Lumina365 throughout over two years of iterative phases.
“We selected pink orange and Polypodium leucotomos due to their well-documented antioxidant and photoprotective properties,” Gotar defined.
“Purple orange extract is wealthy in anthocyanins and flavanones, which assist scale back oxidative stress and assist even pores and skin tone. Polypodium leucotomos, a fern native to Central America, has been studied for its potential to guard pores and skin cells from UV-induced injury and assist immune protection within the pores and skin.”
Collectively, he mentioned, they type a synergistic basis for a day by day complement that reinforces the pores and skin’s pure resilience from inside. The Lumina365 system additionally contains nutritional vitamins A, C, D and E.
Research particulars
The eight week randomized, placebo-controlled, double-blind trial recruited 54 fair-skinned adults (Fitzpatrick phototypes I–III) and assigned them evenly to both a complement or placebo group.
Results on UV tolerance, erythema and pigmentation had been assessed at baseline and a pair of and eight weeks.
General, the findings revealed a 46.2% discount in pores and skin erythema, subsequently demonstrating an anti-inflammatory and photoprotective impact. There was additionally a 23.8% enchancment in Minimal Erythema Dose (MED) reported, which indicated an improved pores and skin tolerance to UVB publicity.
The melanin index confirmed no vital variations in pigmentation between complement and placebo teams, which instructed that the formulation enhanced UV resilience with out affecting tanning response.
Advantages grew to become statistically vital solely after eight weeks of taking the complement.
“These outcomes assist using oral supplementation as an adjunct to topical photoprotection and as a complementary strategy to assist the pores and skin’s pure photoprotective mechanisms, with extended use doubtlessly yielding cumulative advantages,” the researchers reported. “Past their scientific relevance, the findings may assist the event of evidence-based nutraceuticals geared toward enhancing pores and skin resilience to UV-induced injury.”
Though the research was performed in fair-to-medium pores and skin tones, Gotar famous that the mechanisms of motion, antioxidant exercise and assist for the pores and skin’s pure defenses, are usually not unique to anybody pores and skin sort.
“Whereas extra analysis is required to verify advantages throughout the total Fitzpatrick scale, the formulation was designed to be universally supportive of pores and skin uncovered to oxidative stress and UV injury,” he mentioned.
Supply: Vitamins 2025, 17(7), 1240. doi: doi.org/10.3390/nu17071240. “Results of Eight-Week Supplementation Containing Purple Orange and Polypodium leucotomos Extracts on UVB-Induced Pores and skin Responses: A Randomized Double-Blind Placebo-Managed Trial”. Authors: P Keršmanc et al.
