Scientists from the College Hospital of Schleswig-Holstein and the Collagen Analysis Institute in Germany discovered that 2.5 g per day of Verisol B additionally had optimistic medical results on pores and skin elasticity. The ingredient’s advantages had been linked to the stimulatory impact of the bioactive collagen peptides on the synthesis of sort I collagen, elastin and proteoglycans.
Collagen peptides for pores and skin well being
Studies have proven that collagen peptides can enhance pores and skin texture and delay growing older, as they’ll partially survive digestion and accumulate within the pores and skin the place they stimulate the manufacturing of collagen, elastin and proteoglycans by dermal fibroblasts.
These peptides additionally provide antioxidant results and promote cell regeneration, enhancing pores and skin elasticity, hydration and firmness and lowering wrinkles.
Specialists have recognized 28 types of collagen, nonetheless, the physique primarily produces sorts I, II and III, which differ in each composition and placement.
Type I collagen is probably the most plentiful and accounts for about 90% of the physique’s whole collagen. It contributes to the power and elasticity of the pores and skin, tendons, bones and different connective tissues.
Sort II collagen seems primarily in cartilage, the place it supports joint structure and gives flexibility, and type III collagen is discovered within the pores and skin, muscle tissues, blood vessels and inner organs, taking part in a key position in sustaining the integrity of those tissues.
Generally utilized in nutricosmetic formulations, marine collagen is primarily excessive in sort I collagen and is recognized for its high bioavailability. Whereas bovine collagen can be excessive in sort I and sort III collagen, it may be much less bioavailable as a result of its molecular size and amino acid profile.
Examine particulars
Verisol B has been created by making use of an enzymatic hydrolysis course of to bovine sort I collagen. To validate the bovine-specific collagen peptides (SCPs) used within the research, the researchers examined them in vitro on main human dermal fibroblasts.
They confirmed a constant stimulatory impact on the synthesis of sort I collagen, elastin and proteoglycans. The SCPs had been discovered to activate gene and protein expression associated to extracellular matrix manufacturing.
The researchers then recruited 66 ladies between the ages of 35 and 55 for a double-blind, placebo-controlled trial and randomly assigned them to obtain both 2.5 g of SCPs or a placebo day by day for eight weeks.
Members had their eye wrinkle quantity, pores and skin elasticity and hydration measured at baseline, 4 weeks and eight weeks.
Outcomes confirmed that pores and skin elasticity elevated considerably after simply 4 weeks, and by eight weeks, it rose by 9%, with one participant exhibiting a 51% enchancment.
Moreover, after eight weeks, pores and skin hydration elevated by 26%, with an 18% enchancment seen at 4 weeks, and SCP consumption decreased wrinkle quantity by 25% after eight weeks—outperforming the placebo.
In response to the researchers, the outcomes align with earlier analysis on collagen peptides from varied sources.
“The optimistic results on pores and skin moisture and elasticity and the discount in eye wrinkle quantity noticed on this research align with comparable medical research the place comparable pores and skin parameters had been investigated, though not utilizing bovine-derived collagen peptides,” they wrote, noting earlier porcine-derived collagen peptide and fish-derived collagen peptide research additionally discovered comparable results in eye wrinkles, pores and skin moisture and elasticity.
“These information appear to recommend that the medical effectiveness doesn’t primarily rely upon the animal species from which the collagen peptides are derived,” they concluded, calling for additional analysis into whether or not the sources of collagen peptides derived from completely different species have an effect on the efficacy of the product.
Supply: Cosmetics 2025, 12(2), 79; doi: 10.3390/cosmetics12020079. “The Oral Consumption of Particular Bovine-Derived Bioactive Collagen Peptides Has a Stimulatory Impact on Dermal Matrix Synthesis and Improves Numerous Medical Pores and skin Parameters”. Authors: Proksch, E. et al.
