The assessment, revealed within the journal Vitamins, referred to as for a multidimensional method and collaboration amongst specialists to handle knee osteoarthritis and sarcopenia in older individuals. Nutraceuticals similar to vitamin D, amino acids, probiotics and glucosamine sulfate are highlighted as helpful dietary supplements pre-surgery.
Sarcopenia is age-related progressive lack of muscle mass and energy and happens in round 10% of people over age 60 worldwide. Folks with sarcopenia needing surgical procedure have extra danger of issues and fewer favorable outcomes than these with out the situation.
Rising protein consumption by means of meals or dietary supplements and bodily exercise similar to resistance coaching can attenuate muscle loss and enhance energy in sarcopenia. The present assessment was the primary to discover how dietary changes and prehabilitation can enhance surgical outcomes.
Examine particulars
The researchers analyzed 12 randomized managed trials (RCTs) regarding dietary supplementation earlier than knee arthroplasty and 26 scientific trials plus one potential research concerning prehabilitation earlier than the surgical procedure.
They famous a scarcity of research combining prehabilitation and dietary supplementation and that the restricted proof when utilizing the search time period sarcopenia highlights a niche in data and consideration of those elements with regard to knee surgical procedure.
The outcomes instructed that there are at present no standardized prehabilitation and/or dietary supplementation methods particularly tailor-made for sufferers with sarcopenia. Additionally, the kind and period of intervention diversified amongst research.
The authors commented that earlier analysis reveals {that a} affected person’s baseline traits, similar to physique mass index (BMI), bodily operate and stress can predict surgical outcomes. Subsequently, enhancing the presurgical situation might result in higher outcomes following surgical procedure.
The outcomes confirmed that particular dietary supplements could help a greater final result for knee arthroplasty. These embody vitamin D, important amino acids (EAAs), iron, glucosamine sulfate and adenosine triphosphate.
Helpful prehabilitation methods embody energy coaching, flexibility, cardio train, endurance coaching, proprioceptive workouts, blood move restriction workouts, neuromuscular and postural workouts, and acupuncture.
Vitamin and sarcopenia
Sarcopenia develops throughout growing old because of insufficient vitamin, a sedentary way of life, irritation and hormonal and neurological alterations. Folks with knee osteoarthritis who’ve restricted mobility are vulnerable to succumbing to sarcopenia and will require surgical procedure.
Sarcopenic sufferers typically have decrease protein, vitamin D, and micronutrient consumption, which negatively impacts muscle well being. Subsequently, managing sarcopenia requires a multimodal method involving correct vitamin, anti-inflammatory and anabolic medicines, and rehabilitation coaching.
Satisfactory protein is essential to stop muscle loss. The present assessment recommends that wholesome people want 1 g to 1.2 g of protein per kilogram of physique weight per day (g/kg/d), and other people with sickness or malnutrition require increased quantities of 1.2 g to 1.5 g.
A 2013 study instructed that EAAs earlier than and two weeks after knee arthroplasty attenuated muscle atrophy and accelerated the return of practical mobility.
The present assessment notes that probiotics could help muscle energy, however human analysis is missing, and {that a} complement mixture of protein, leucine, vitamin D and n-3 polyunsaturated fat (PUFAs) earlier than orthopedic surgical procedure could stop sarcopenia and practical deterioration. The researchers additionally spotlight vitamin D’s position in bone well being and muscle energy.
The researchers referred to as for additional investigations in older populations with sarcopenia to advertise the event of customized dietary methods.
Supply: Vitamins 2024, 16(20), 3462;
doi: 10.3390/nu16203462
“Optimizing the preoperative preparation of sarcopenic older individuals: The position of prehabilitation and dietary supplementation earlier than knee arthroplasty.”
Authors: F. Pegreffi et al.
