Launched in 2022, Dermial’s hero ingredient is a high-concentration hyaluronic acid, a naturally occurring substance within the human physique that’s primarily discovered within the pores and skin, eyes and connective tissues. It’s a kind of glycosaminoglycan (GAG) and is greatest recognized for its skill to retain moisture because it is ready to maintain as much as 1,000 occasions its weight in water. The hyaluronic acid matrix (HAm) formulation additionally comprises dermatan sulfate and collagen to maintain pores and skin nourished and hydrated.
In line with Antonio Vendrell, advertising and marketing and communications director at Bioiberica, shoppers are waking as much as hyaluronic acid dietary supplements as a rising physique of proof hyperlinks pores and skin growing older to weight-reduction plan.
“As an increasing number of shoppers acknowledge that wholesome and glowing pores and skin is the results of a nutritious diet, many are actually searching for magnificence dietary supplements to help this,” he instructed NutraIngredients.
Market analysis agency Priority Analysis estimated the worldwide hyaluronic acid market measurement to be US$ 11.14 billion in 2024, with US$ 2,363.7 million of that attributed to hyaluronic complement gross sales (Future Market Insights).
Ageless magnificence
Performed by Bioiberica and revealed in Dermatology and Remedy, Vendrell mentioned the brand new analysis “confirms the medical impact of Dermial, the primary hyaluronic acid matrix ingredient for pores and skin and sweetness.”
Whereas the outcomes confirmed that intervention improved pores and skin look markers throughout ages within the group of 60 wholesome ladies between the ages of 35 and 60, individuals over the age of 55 confirmed important enhancements at earlier time factors in comparison with youthful individuals.
This included enhancements throughout many pores and skin barrier perform parameters, together with brightness/glow, hydration, deformability, smoothness, roughness, scaliness and temperature.
“These new findings recommend Dermial can deal with age-related pores and skin issues, akin to the looks of wrinkles and high-quality traces, dryness, dullness, roughness and lack of firmness, by enhancing the pores and skin’s barrier perform and microtopography,” Vendrell mentioned.
In line with Euromonitor’s newest Voice of the Shopper: Well being and Diet Survey, 27% of worldwide respondents ages 45 to 59 reported utilizing nutritional vitamins and dietary dietary supplements particularly for magnificence and pores and skin well being, up from 25% in 2024.
“This rising adoption amongst older demographics highlights the increasing attraction of magnificence dietary supplements past youthful shoppers and underscores the shift in direction of extra holistic approaches to well being and wellness throughout age teams,” Aishwarya Rajpara, well being and sweetness marketing consultant at Euromonitor Worldwide, instructed NI.
Oral hyaluronic acid improves pores and skin hydration
The randomized, double-blind, placebo-controlled medical trial was performed on the Dermatology Division of Hospital Universitario Virgen de las Nieves de Granada.
It assigned ladies with pure indicators of facial growing older to devour both a each day dose of 60 mg of Dermial or a placebo for 12 weeks. A dermatologist evaluated individuals at baseline, week six and week 12.
Researchers evaluated pores and skin parameters akin to hydration, temperature, pH, elasticity, erythema and melanin. They assessed brightness, deformability, friction and pores and skin hardness and measured antioxidant capability through electrochemical strategies. Additionally they assessed pores and skin floor parameters together with smoothness, roughness, scaliness and wrinkles.
Findings indicated that each day individuals within the supplementation group skilled enhanced pores and skin hydration, brightness, smoothness and decreased roughness, wrinkles, scaliness and erythema.
Supplementation with Dermial was additionally discovered to spice up pores and skin hydration, significantly within the periocular space and cheek, supporting present analysis on hyaluronic acid’s water-retention capability. It additionally elevated pores and skin brightness, which the research attributes to higher hydration, decreased redness and smoother pores and skin texture.
As well as, the researchers famous that an noticed lower in pores and skin temperature is probably going resulting from improved hydration and barrier perform since well-hydrated pores and skin tends to retain extra water and lose much less by means of evaporation—leading to a decrease floor temperature.
They highlighted the findings as novel for orally administered hyaluronic acid, as earlier proof centered primarily on injected therapies.
“HAm’s distinctive skill to extend pores and skin brightness/glow is important, as pores and skin brightness is a key indicator of wholesome and youthful pores and skin,” they wrote.
“No earlier medical trials have evaluated the impression of oral HA on this pores and skin property, however beforehand it has been noticed that mesotherapy with HA can enhance pores and skin brightness.”
Journal: Dermatology and Remedy. “Supplementation with a New Hyaluronic Acid Matrix Ingredient Improves Pores and skin Brightness, Hydration, Smoothness, and Roughness: Outcomes from a Randomized, Double-Blinded, Placebo-Managed Examine”. doi: 10.1007/s13555-025-01447-6. Authors: Montero-Vilchez, T. et al..
