The IMMUSE postbiotic Lactococcus lactis pressure Plasma, which received the 2023 NutraIngredients-USA Microbiome Modulation ingredient of the yr award, is reported to activate key immune cells known as plasmacytoid dendritic cells (pDCs), that are key drivers of the immune system and stimulate each innate and adaptive immune responses.
The ingredient was developed by Kirin Holdings and Kyowa Hakko andsupported by a portfolio of science, together with 15 scientific research demonstrating its efficacy in supporting immune well being.
Information from a 2016 randomized scientific trial indicated that heat-killed L. lactis considerably decreased the variety of cough days and sore throat severity associated to the widespread chilly and influenza in younger wholesome adults (Shibata, 2016). A subsequent randomized managed double-blind research with 111 contributors reported that the postbiotic was related to enhanced immune response, together with up-regulation of antiviral gene expression ranges and elevated secreted IgA ranges in saliva (Fujii, 2017).
There may be additionally a sports activities diet alternative for IMMUSE, with information from research in wholesome athletes indicating that the ingredient could promote train efficiency by supporting the immune system (Komano, 2018 and 2023).
As well as, the postbiotic has been reported to supply pores and skin well being advantages (Fujii, 2021 and Tsuji, 2021).
“With 90 years of experience in microbial options, we provide science-backed, custom-made probiotic and postbiotic formulation for dietary dietary supplements, meals and beverage functions and pet dietary supplements,” stated Isabelle Champié, vice chairman of gross sales and advertising at Lallemand Well being Options. “IMMUSE from Kirin Holdings might be an awesome addition to our portfolio, bringing a documented answer for immune well being to fulfill the growing market demand.”
Postbiotics
Postbiotics have been outlined by the Worldwide Scientific Affiliation of Probiotics and Prebiotics (ISAPP) as a “preparation of inanimate microorganisms and/or their parts that confers a well being profit on the host” (Salminen, 2021).
In keeping with Lallemand, the postbiotic dietary supplements market was estimated to be US$10.8 million in 2024 and projected to develop at a CAGR of 10.9% to achieve US$ 30.5 million by 2034.
