Launched with the tagline ‘No gimmicks—simply actual science’, Management is designed to naturally help GLP-1 ranges, scale back cravings and increase metabolism in girls navigating the metabolic challenges of midlife from peri to put up menopause.
The complement accommodates clinically studied substances together with Eriomin (a lemon bioflavonoid advanced) and Siliphos (milk thistle extract) which offer help for important organs such because the liver and thyroid.
This units Management aside from its rivals, based on Alexander Pilawski, innovation supervisor and vitamin scientist at Elénzia, who says the complement presents a “systemic strategy” to supporting the physique’s pure drive to stability glycemia.
“Management enters the market at a time the place harnessing glycemic administration as a software for weight reduction and metabolic well being is at an all-time excessive,” he advised NutraIngredients. “Because the market turns into an increasing number of saturated, you will need to present distinguishing components that carve out a distinct segment.”
“At Elénzia, our ethos guides us to suppose holistically concerning the problem at hand to offer an answer that’s multifaceted and tailor-made to our demographic’s distinctive wants,” he added.
Supporting the liver and thyroid
Management joins the corporate’s current vary of dietary supplements for menopause, cognition, joint well being and immunity.
Pilawski described Eriomin at Elénzia’s hero ingredient, noting that its advantages have been demonstrated in three randomized, double-blind, placebo-controlled human scientific trials.
“These research, which concerned over 170 prediabetic sufferers, offered some actually compelling outcomes [at a] low dose of solely 200 mg/day,” he stated. “After 12 weeks of supplementation, members had considerably elevated GLP-1 ranges, as high as 22%.”
“The icing on the cake for me is the discount in fasting blood glucose ranges by 6.5%, and in a single examine, the reversal of prediabetes in 24% of participants with out way of life adjustments. I can solely think about how potent this may very well be with dietary and train enhancements,” he added.
Comparatively, Siliphos, a standardized silybin-phosphatidylcholine advanced, protects and helps liver perform by enhancing glutathione ranges, enhancing antioxidant safety, supporting bile circulation and optimizing fats metabolism.
“Liver well being is essential for numerous metabolic processes, and it’s a rising concern as we see the worldwide prevalence of Non-Alcoholic Fatty Liver Illness (NAFLD) now affecting over 1 / 4 of girls worldwide,” Pilawski defined. “As there’s a bi-directional relationship between liver well being and glucose homeostasis, supporting liver well being and performance is crucial, particularly main as much as and all through the menopausal expertise the place NAFLD danger is even larger.”
Management additionally accommodates a “extremely bioavailable” mineral advanced to help thyroid hormone synthesis, which is an “underappreciated concern amongst menopausal girls,” based on Pilawski.
This advanced consists of iodine for thyroid hormone synthesis, selenium to help the conversion of T4 to energetic T3 hormones, and zinc for insulin and TSH (thyroid-stimulating hormone) signalling and T3 receptor sensitivity.
A multi-faceted strategy
Management is subsequently offered as a multi-faceted strategy to weight administration, with every ingredient chosen to enhance one another mechanistically.
“There are a number of mechanisms at play, however the core ones embody potent antioxidant and anti inflammatory actions that improve mobile insulin sensitivity,” Pilawski stated. “Moreover, the stimulation of intestinal L-cells by these citrus flavonoids will increase native GLP-1 manufacturing, a key participant in glucose administration. Our botanical substances additionally modulate the microbiome, selling normoglycaemia over time.”
To check the impact of the mixture of substances utilized in Management, Elénzia is at present conducting a pilot examine which can function a foundation for a full-scale way of life examine, with outcomes anticipated within the close to future.
