Magshape, a micronized and microencapsulated supply of magnesium, was proven to raise blood magnesium ranges for a minimum of six hours—longer than any of the opposite types examined within the research.
“Magshape microcapsules [are] a bioavailable and well-tolerated various to current magnesium-based elements utilized in meals dietary supplements,” wrote researchers from Bionos Biotech and Lubrizol Life Science.
The analysis, revealed within the journal Vitamins, was funded by Lubrizol, which manufactures the product.
Magnesium deficiency frequent in European populations
Magnesium is a necessary mineral, performing as a co-factor in additional than 600 enzymatic reactions within the physique. It’s significantly vital for sustaining regular muscle and nerve operate, regulating blood glucose ranges and irritation, and contributing to the structural improvement of bones.
Nevertheless, magnesium deficiency is frequent in European populations. That is partly because of diet-related elements and soil degradation, however absorption points additionally play a key function.
Certainly, charges of magnesium absorption might be as little as 10% relying on the kind of magnesium and formulation elements, with magnesium oxide having one of many poorest absorption charges.
“A number of elements have an effect on magnesium absorption,” mentioned Alan Connolly, analysis and improvement supervisor at Lubrizol. “The presence of different vitamins is one such issue; some vitamins, like proteins, sugars, MCT or vitamin D, improve absorption, whereas excessive doses of zinc, sulphates or oxalates can inhibit it.”
“The pH of the digestive tract additionally performs a vital function. The abdomen’s acidity or alkalinity impacts absorption, with sure types of magnesium being extra soluble in acidic environments,” he advised NutraIngredients.
Magshape: why microencapsulation?
To beat this, Lubrizol launched Magshape, a microencapsulated magnesium oxide, particularly designed to reinforce the mineral’s bioavailability.
The microencapsulation course of entails packaging magnesium in a protecting matrix, which minimizes interactions with different energetic elements and environmental elements.
“Magnesium salts can work together with nutritional vitamins and botanicals when mixed in the identical product, leading to decreased exercise and decrease bioavailability,” Connolly mentioned. “By microencapsulating the magnesium in a protecting shell, this drawback is prevented.”
Microencapsulation additionally leads to a extra nice sensory expertise, Connolly added. The method, which doesn’t chemically modify the magnesium itself, removes the sturdy style related to magnesium salts leading to higher total person satisfaction.
A gentler launch
The research concerned 40 wholesome women and men, every of whom have been placed on a low magnesium weight loss program for seven days.
Individuals have been randomized to obtain one among 4 several types of magnesium (every at a 375 mg dose) each week, with blood samples obtained at baseline and one, 4 and 6 hours after oral consumption.
Magshape microcapsules have been in comparison with the uncooked types of magnesium oxide, citrate and bisglycinate—essentially the most generally used magnesium sources in meals dietary supplements.
Lubrizol’s microcapsules have been discovered to considerably elevate blood magnesium ranges in any respect examined time factors, with excessive ranges maintained for as much as six hours post-intake.
These outcomes weren’t seen in individuals taking the uncooked types of magnesium oxide, citrate and bisglycinate, indicating their incapability to successfully induce sustained elevation of magnesium ranges.
Individuals taking Magshape additionally reported fewer antagonistic occasions, together with decreased bowel exercise and gastric ‘heaviness’, each of that are frequent unwanted effects of magnesium supplementation.
“Microencapsulation can reduce these unwanted effects by guaranteeing a gentler launch within the digestive tract,” Connolly mentioned. “This additionally ensures that magnesium is launched within the appropriate space and might be absorbed by the physique as wanted.”
Supply: Vitamins. doi: 10.3390/nu16244367. “Comparative Scientific Examine on Magnesium Absorption and Aspect Results After Oral Consumption of Microencapsulated Magnesium (MAGSHAPETM Microcapsules) Versus Different Magnesium Sources.“ Authors: Pajuelo, D. et al.
