The Lithuanian model, launched in 2020, launched its inaugural product after 10 years of improvement, Diana Zasimauskienė, model supervisor, informed NutraIngredients.
Founder Rima Balanaskiene, a pharmaceutical investor and former TV character, started her mission to focus on indicators of getting older when she felt disappointment with what she noticed of herself on digital camera. She set about assembling a worldwide workforce of scientists specializing in epigenetics and labored with Cambridge College biogerontologists targeted on the Methods for Engineered Negligible Senescence (SENS) concept.
The analysis workforce discovered that 80% of getting older outcomes from exterior components like food plan, stress and life-style, whereas solely 20% connects to genetics. This perception led to the event of NoAGE, a product designed not simply to deal with the signs of getting older however to regenerate and restore cells at their core.
The product, developed in Switzerland, goals to delay the indicators of getting older each internally and externally, utilizing a complete mix of capsules and vials designed to work synergistically to help mobile rejuvenation, enhance immunity and promote total well-being.
SENS concept
SENS is a theoretical framework aimed toward reversing getting older by repairing key varieties of molecular and mobile injury that accumulate with age.
The controversial technique focuses on reversing the mechanisms of getting older, using potential future applied sciences like stem cell remedy, gene remedy and enzyme remedies, with out a full mechanistic understanding.
Critiques of SENS have argued that the complexity of organic programs and the dearth of confirmed applied sciences render the proposal overly optimistic.
The weekday routine
NoAGE’s answer is a five-day complement program, priced at £249 per thirty days provide, with every weekday focusing on a special organic course of associated to getting older.
Every day, customers take a pair of dietary supplements—a capsule and a vial—designed to stimulate particular mobile features.
Monday focuses on antioxidation and combating oxidative stress with elements like grapevine seed extract and pomegranate. This present day helps steadiness free radicals within the physique, which may speed up getting older.
Tuesday targets glucose regulation, aiming to handle blood sugar ranges and forestall collagen-elastin cross-linking. This complement aids in pure collagen manufacturing, selling pores and skin elasticity and lowering wrinkles.
Wednesday’s complement focuses on lowering persistent irritation, a key think about many long-term well being points, together with cardiovascular illnesses. A clinical trial additionally confirmed that the routine diminished irritation by 41% and pores and skin redness by 14%.
Thursday is for telomere regeneration. Telomeres, protecting caps on the ends of chromosomes, naturally shorten with age. NoAGE goals to sluggish this course of to advertise mobile longevity.
Friday is about boosting the immune system and strengthening the physique’s defenses towards infections and autoimmune illnesses, which change into extra widespread with age.
Every product combines aligning herbs, nutritional vitamins and minerals, and the capsule-vial mixture makes the method extra manageable and nice for customers, Zasimauskienė defined, noting that it ensures most efficacy with minimal discomfort.
“If it have been all in capsule type, customers would want to take 80 drugs per day—it’s very unrealistic,” she added.
As an alternative, NoAGE has break up the formulation, inserting the extra bitter elements in capsules and the extra pleasant-tasting ones in vials, lowering the day by day consumption to only one day by day capsule and enhancing the person expertise.
Market enlargement
NoAGE primarily targets ladies between the ages of 40 and 60, a demographic that already focuses on vitamin, health and longevity, Zasimauskienė defined.
Nevertheless, after the primary launch and additional analysis, the corporate refined its product line in 2022 to cater particularly to males and post-menopausal ladies, addressing the hormonal variations and particular getting older challenges every gender faces.
As an illustration, the product for males presents related advantages, with added emphasis on bodily efficiency, vitality and sexual vitality.
The model has expanded into a number of worldwide markets, providing its merchandise within the UK, the Baltics, the UAE, Italy, China, Romania and Germany. It is usually within the strategy of registering the product in Mexico.
However as Zasimauskienė famous, getting into new markets is troublesome on account of differing international rules.
“Every NoAGE product accommodates 40 elements in comparison with the everyday 10 present in most dietary supplements,” she stated. “Which means navigating prolonged registration processes required for worldwide enlargement.”
